| Pos. | Edition | Number of different leaders | Leaders |
|---|
| 1 | 2011 | 9 | Cobo, Froome, Bennati, Lastras, Fuglsang, Wiggins, Mollema, Chavanel, Rodríguez |
| 2 | 2008 | 8 | Martinez, Ballan, Chavanel, Leipheimer, Contador, Valverde, Bennati, Pozzato |
| 3 | 1960 | 7 | Mulder, Barrutia, Alberdi, Mas, Desmet, Galdeano, Manzaneque |
| 4 | 1964 | 7 | Otano, Looy, Pérez, Sels, Vélez, Jiménez, Poulidor |
| 5 | 1967 | 7 | Ducasse, Dancelli, Uriona, Janssen, López, Perurena, Reybrouck |
| 6 | 1957 | 6 | Chacon Diez, Loroño, Moreno, Bahamontes, Botella, Morales |
| 7 | 1958 | 6 | Groot, Pacheco, Couvreur, Stablinski, Berrendero, Looy |
| 8 | 1959 | 6 | Segu, Vloebergs, Everaert, Suarez, Looy, Karmany |
| 9 | 1961 | 6 | Talamillo, Mahé, Vélez, Messelis, Seynaeve, Soler |
| 10 | 1966 | 6 | Uriona, Gabica, Errandonea, Haast, Sivilotti, Momene |
| 11 | 1968 | 6 | Gimondi, Pérez, Janssen, Martin, Altig, Wright |
| 12 | 1969 | 6 | Wright, Ocana, Steegmans, Saéz, Sgarbozza, Pingeon |
| 13 | 1976 | 6 | Pesarrodona, Agostinho, Elorriaga, Thurau, Cauwer, Kuiper |
| 14 | 1983 | 6 | Gaigne, Pino, Fernández, Hinault, Gorospe, Lejarreta |
| 15 | 1989 | 6 | Lameire, Delgado, Hernandez, Leclerc, Farfán, Brabant |
| 16 | 2006 | 6 | Brajkovič, Hushovd, Valverde, Luca, Vinokourov, Sastre |
| 17 | 2016 | 6 | Cruz, Kennaugh, Quintana, Fernández, Kwiatkowski, Atapuma |
| 18 | 1946 | 5 | Olmos, Langarica, Martín, Costa, Rodríguez |
| 19 | 1955 | 5 | Bauvin, Marigil, Loroño, Geminiani, Dotto |
| 20 | 1971 | 5 | Perurena, Bracke, Tamames, Pijnen, Lasa |
| 21 | 1985 | 5 | Oosterbosch, Indurain, Ruiz, Delgado, Millar |
| 22 | 1986 | 5 | Blanco, Pino, Millar, Gomez, Marie |
| 23 | 1987 | 5 | Pagnin, Vandenbroucke, Dietzen, Kelly, Herrera |
| 24 | 1997 | 5 | Guidi, Zülle, Dufaux, Michaelsen, Jalabert |
| 25 | 1998 | 5 | Zberg, Olano, Jalabert, Guidi, Jimenez |
| 26 | 1999 | 5 | Durand, Gonzalez De Galdeano, Wüst, Ullrich, Olano |
| 27 | 2000 | 5 | Gonzalez, Casero, Zülle, Heras, Olano |
| 28 | 2001 | 5 | Sevilla, Casero, Millar, Beloki, Botero |
| 29 | 2002 | 5 | Beloki, Zarrabeitia, Sevilla, Gonzalez Jimenez, Heras |
| 30 | 2004 | 5 | Beltran, Joachim, Heras, Landis, Heeswijk |
| 31 | 2007 | 5 | Efimkin, Menchov, Freire, Bennati, Devolder |
| 32 | 2010 | 5 | Nibali, Rodríguez, Gilbert, Anton, Cavendish |
| 33 | 2013 | 5 | Roche, Horner, Nibali, Brajkovič, Moreno |
| 34 | 2014 | 5 | Valverde, Contador, Castroviejo, Quintana, Matthews |
| 35 | 2015 | 5 | Velits, Chaves, Dumoulin, Rodríguez, Aru |
| 36 | 1948 | 4 | Gielen, Ruiz, Langarica, Berrendero |
| 37 | 1970 | 4 | Ocana, Perurena, Tamames, Pijnen |
| 38 | 1972 | 4 | Fuente, Pijnen, Lasa, Perurena |
| 39 | 1974 | 4 | Swerts, Perurena, Fuente, Thévenet |
| 40 | 1975 | 4 | Perurena, Tamames, Swerts, Lasa |
| 41 | 1982 | 4 | Criquielion, Arroyo, Gomez, Lejarreta |
| 42 | 1988 | 4 | Fuerte Abelenda, Kelly, Pastorelli, Cubino |
| 43 | 1990 | 4 | Ruiz, Klimov, Giovannetti, Gorospe |
| 44 | 1992 | 4 | Rominger, Ruiz, Nijdam, Montoya |
| 45 | 1996 | 4 | Zülle, Baldato, Jalabert, Conte |
| 46 | 2003 | 4 | Gonzalez De Galdeano, Heras, Nozal Vega, Rodríguez |
| 47 | 2009 | 4 | Cancellara, Valverde, Evans, Greipel |
| 48 | 2012 | 4 | Rodríguez, Valverde, Castroviejo, Contador |
| 49 | 1935 | 3 | Escuriet, Deloor, Dignef |
| 50 | 1941 | 3 | Rodríguez, Trueba, Berrendero |
| 51 | 1947 | 3 | Rodríguez, Dijck, Costa |
| 52 | 1962 | 3 | Elliott, Barrutia, Altig |
| 53 | 1965 | 3 | Looy, Wolfshohl, Poulidor |
| 54 | 1973 | 3 | Merckx, Karstens, Pesarrodona |
| 55 | 1984 | 3 | Caritoux, Delgado, Moser |
| 56 | 1991 | 3 | Mauri, Fuerte Abelenda, Diaz |
| 57 | 1995 | 3 | Olano, Jalabert, Pianegonda |
| 58 | 2005 | 3 | Menchov, Heras, McGee |
| 59 | 2017 | 3 | Lampaert, Dennis, Froome |
| 60 | 1936 | 2 | Huts, Deloor |
| 61 | 1945 | 2 | Rodríguez, Berrendero |
| 62 | 1950 | 2 | Rodríguez, Braekevelt |
| 63 | 1956 | 2 | Steenbergen, Conterno |
| 64 | 1963 | 2 | Anquetil, Barrutia |
| 65 | 1978 | 2 | Hinault, Haute |
| 66 | 1979 | 2 | Zoetemelk, Levavasseur |
| 67 | 1980 | 2 | Visentini, Rupérez |
| 68 | 1981 | 2 | Battaglin, Clère |
| 69 | 1993 | 2 | Rominger, Zülle |
| 70 | 1942 | 1 | Berrendero |
| 71 | 1977 | 1 | Maertens |
| 72 | 1994 | 1 | Rominger |
