| 1 | 2008-03-08 | 1 | Monte Paschi Eroica | 1.1 | 3057 |
| 2 | 2012-03-03 | 1 | Montepaschi Strade Bianche - Eroica Toscana | 1.1 | 2933 |
| 3 | 2016-03-05 | 1 | Strade Bianche | 1.HC | 2907 |
| 4 | 2014-04-06 | 1 | Ronde van Vlaanderen / Tour des Flandres ME | 1.UWT | 2095 |
| 5 | 2013-03-31 | 1 | Ronde van Vlaanderen / Tour des Flandres ME | WT | 2066 |
| 6 | 2010-04-11 | 1 | Paris - Roubaix | 1.HC | 1937 |
| 7 | 2006-04-09 | 1 | Paris - Roubaix | 1.PT | 1933 |
| 8 | 2013-03-22 | 1 | E3 Prijs Vlaanderen - Harelbeke | WT | 1899 |
| 9 | 2010-04-04 | 1 | Ronde van Vlaanderen / Tour des Flandres ME | PT | 1642 |
| 10 | 2007-07-10 | 1 | Tour de France | Stage 3 | 2.PT | 1397 |
| 11 | 2013-04-07 | 1 | Paris - Roubaix | WT | 997 |
| 12 | 2008-08-13 | 1 | Olympic Games - ITT | Olympics | 992 |
| 13 | 2016-08-10 | 1 | Olympic Games - ITT | Olympics | 857 |
| 14 | 2013-09-04 | 1 | Vuelta a España | Stage 11 (ITT) | WT | 687 |
| 15 | 2010-09-30 | 1 | World Championships ME - ITT | WC | 557 |
| 16 | 2007-09-27 | 1 | World Championships ME - ITT | WC | 513 |
| 17 | 2006-09-21 | 1 | World Championships ME - ITT | WC | 462 |
| 18 | 2008-07-26 | 1 | Tour de France | Stage 20 (ITT) | 2.HC | 408 |
| 19 | 2009-09-24 | 1 | World Championships ME - ITT | WC | 390 |
| 20 | 2009-07-04 | 1 | Tour de France | Stage 1 (ITT) | 2.HC | 316 |
| 21 | 2004-07-03 | 1 | Tour de France | Prologue | GT | 177 |
| 22 | 2010-07-24 | 1 | Tour de France | Stage 19 (ITT) | 2.HC | 167 |
| 23 | 2011-08-20 | 1 | Vuelta a España | Stage 1 (TTT) | WT | 154 |
| 24 | 2012-06-30 | 1 | Tour de France | Prologue | WT | 79 |
| 25 | 2016-06-11 | 1 | Tour de Suisse | Stage 1 (ITT) | 2.UWT | 46 |
| 26 | 2010-07-03 | 1 | Tour de France | Prologue | 2.HC | 43 |
| 27 | 2009-09-05 | 1 | Vuelta a España | Stage 7 (ITT) | 2.HC | 40 |
| 28 | 2007-07-07 | 1 | Tour de France | Prologue | 2.PT | 33 |
| 29 | 2016-03-15 | 1 | Tirreno-Adriatico | Stage 7 (ITT) | 2.UWT | 16 |
| 30 | 2009-08-29 | 1 | Vuelta a España | Prologue | 2.HC | 13 |
| 31 | 2006-08-26 | 1 | Vuelta a España | Stage 1 (TTT) | 2.PT | 9 |
| 32 | 2011-03-15 | 1 | Tirreno-Adriatico | Stage 7 (ITT) | WT | 8 |
| 33 | 2015-03-17 | 1 | Tirreno-Adriatico | Stage 7 (ITT) | 2.UWT | 8 |
| 34 | 2012-03-13 | 1 | Tirreno-Adriatico | Stage 7 (ITT) | WT | 6 |
| 35 | 2011-06-19 | 1 | Tour de Suisse | Stage 9 (ITT) | WT | |
| 36 | 2011-06-11 | 1 | Tour de Suisse | Prologue | WT | |
| 37 | 2011-06-01 | 1 | Škoda-Tour de Luxembourg | Prologue | 2.HC | |
| 38 | 2011-03-26 | 1 | E3 Prijs Vlaanderen | 1.HC | |
| 39 | 2013-06-19 | 1 | National Championships Switzerland ME - ITT | NC | |
| 40 | 2008-03-18 | 1 | Tirreno-Adriatico | General classification | WT | |
| 41 | 1999-05-11 | 1 | Course de la Paix Juniors | General classification | | |
| 42 | 1999-10-05 | 1 | World Championships MJ - ITT | WC | |
| 43 | 2004-06-23 | 1 | National Championships Switzerland ME - ITT | NC | |
| 44 | 2000-04-09 | 1 | National Championships Switzerland MU - ITT | NC | |
| 45 | 2011-06-26 | 1 | National Championships Switzerland ME - Road Race | NC | |
| 46 | 2002-02-24 | 1 | International Tour of Rhodes | General classification | 2.3 | |
| 47 | 2008-06-04 | 1 | Škoda-Tour de Luxembourg | Prologue | 2.HC | |
| 48 | 2006-05-15 | 1 | Volta Ciclista a Catalunya | Stage 1 (ITT) | 2.PT | |
| 49 | 2006-03-12 | 1 | Tirreno-Adriatico | Stage 5 (ITT) | 2.PT | |
| 50 | 2012-06-20 | 1 | National Championships Switzerland ME - ITT | NC | |