| 1 | 2021-03-07 | GP Industria & Artigianato | 1.Pro |
| 2 | 2021-03-21 | Per Sempre "Alfredo" | 1.1 |
| 3 | 2021-03-23 | Settimana Internazionale Coppi e Bartali | 2.1 |
| 4 | 2021-05-29 | Orlen Nations Grand Prix | 2.Ncup |
| 5 | 2021-06-03 | Course de la Paix Grand Prix Jeseníky | 2.Ncup |
| 6 | 2021-06-15 | Adriatica Ionica Race / Sulle Rotte della Serenissima | 2.1 |
| 7 | 2021-06-24 | Giro dell'Appennino | 1.1 |
| 8 | 2021-07-04 | Giro del Medio Brenta | 1.2 |
| 9 | 2021-07-08 | Baloise Ladies Tour | 2.1 |
| 10 | 2021-07-14 | Settimana Ciclistica Italiana | 2.1 |
| 11 | 2021-07-19 | L'Etoile d'Or | 2.Ncup |
| 12 | 2021-07-24 | Olympic Games ME - Road Race | Olympics |
| 13 | 2021-07-25 | Olympic Games WE - Road Race | Olympics |
| 14 | 2021-07-28 | Olympic Games ME - ITT | Olympics |
| 15 | 2021-07-28 | Olympic Games WE - ITT | Olympics |
| 16 | 2021-08-13 | Tour de l'Avenir | 2.Ncup |
| 17 | 2021-08-26 | Course de la Paix Juniors | 2.Ncup |
| 18 | 2021-09-02 | Giro della Lunigiana | 2.1 |
| 19 | 2021-09-08 | European Continental Championships - Mixed Relay TTT | CC |
| 20 | 2021-09-08 | European Continental Championships MJ - ITT | CC |
| 21 | 2021-09-08 | European Continental Championships WJ - ITT | CC |
| 22 | 2021-09-09 | European Continental Championships ME - ITT | CC |
| 23 | 2021-09-09 | European Continental Championships WE - ITT | CC |
| 24 | 2021-09-09 | European Continental Championships MU - ITT | CC |
| 25 | 2021-09-09 | European Continental Championships WU - ITT | CC |
| 26 | 2021-09-10 | European Continental Championships MJ - Road Race | CC |
| 27 | 2021-09-10 | European Continental Championships WU - Road Race | CC |
| 28 | 2021-09-10 | European Continental Championships WJ - Road Race | CC |
| 29 | 2021-09-11 | European Continental Championships WE - Road Race | CC |
| 30 | 2021-09-11 | European Continental Championships MU - Road Race | CC |
| 31 | 2021-09-12 | European Continental Championships ME - Road Race | CC |
| 32 | 2021-09-15 | Giro della Toscana - Memorial Alfredo Martini | 1.1 |
| 33 | 2021-09-16 | Coppa Sabatini - Gran Premio città di Peccioli | 1.Pro |
| 34 | 2021-09-18 | Memorial Marco Pantani | 1.1 |
| 35 | 2021-09-19 | Trofeo Matteotti | 1.1 |
| 36 | 2021-09-19 | World Championships ME - ITT | WC |
| 37 | 2021-09-20 | World Championships WE - ITT | WC |
| 38 | 2021-09-20 | World Championships MU - ITT | WC |
| 39 | 2021-09-21 | World Championships MJ - ITT | WC |
| 40 | 2021-09-21 | World Championships WJ - ITT | WC |
| 41 | 2021-09-22 | World Championships - Mixed Relay TTT | WC |
| 42 | 2021-09-24 | World Championships MU - Road Race | WC |
| 43 | 2021-09-24 | World Championships MJ - Road Race | WC |
| 44 | 2021-09-25 | World Championships WE - Road Race | WC |
| 45 | 2021-09-25 | World Championships WJ - Road Race | WC |
| 46 | 2021-09-26 | World Championships ME - Road Race | WC |
| 47 | 2021-10-03 | Il Piccolo Lombardia | 1.2U |
| 48 | 2021-10-11 | Coppa Agostoni - Giro delle Brianze | 1.1 |
| 49 | 2021-10-13 | Giro del Veneto | 1.1 |
| 50 | 2021-10-17 | Veneto Classic | 1.1 |