| 1 | 2021-02-27 | Omloop Het Nieuwsblad WE | 1.Pro |
| 2 | 2021-03-02 | Le Samyn des Dames | 1.1 |
| 3 | 2021-03-06 | Strade Bianche Donne | 1.WWT |
| 4 | 2021-03-10 | Healthy Ageing Tour | 2.1 |
| 5 | 2021-03-14 | GP Oetingen | 1.2 |
| 6 | 2021-03-17 | Danilith Nokere Koerse WE | 1.Pro |
| 7 | 2021-03-21 | Trofeo Alfredo Binda - Comune di Cittiglio | 1.WWT |
| 8 | 2021-03-25 | Oxyclean Classic Brugge-De Panne WE | 1.WWT |
| 9 | 2021-03-28 | Gent-Wevelgem In Flanders Fields WE | 1.WWT |
| 10 | 2021-03-31 | Dwars door Vlaanderen - A travers la Flandre WE | 1.1 |
| 11 | 2021-04-04 | Ronde van Vlaanderen - Tour des Flandres WE | 1.WWT |
| 12 | 2021-04-05 | Ronde de Mouscron | 1.1 |
| 13 | 2021-04-07 | Scheldeprijs WE | 1.1 |
| 14 | 2021-04-14 | De Brabantse Pijl - La Flèche Brabançonne WE | 1.1 |
| 15 | 2021-04-18 | Vuelta CV Feminas | 1.1 |
| 16 | 2021-04-18 | Amstel Gold Race Ladies Edition | 1.WWT |
| 17 | 2021-04-21 | La Flèche Wallonne Féminine | 1.WWT |
| 18 | 2021-04-25 | Liège-Bastogne-Liège Femmes | 1.WWT |
| 19 | 2021-04-30 | Ceratizit Festival Elsy Jacobs | 2.Pro |
| 20 | 2021-05-06 | V Setmana Ciclista Valenciana - Vuelta Comunitat Valenciana Feminas | 2.1 |
| 21 | 2021-05-13 | Emakumeen Nafarroako Women's Elite Classics | 1.1 |
| 22 | 2021-05-14 | Navarra Women's Elite Classics | 1.1 |
| 23 | 2021-05-16 | Gran Premio Ciudad de Eibar | 1.1 |
| 24 | 2021-05-18 | Durango - Durango Emakumeen Saria | 1.1 |
| 25 | 2021-05-20 | Vuelta a Burgos Feminas | 2.WWT |
| 26 | 2021-05-25 | Internationale LOTTO Thüringen Ladies Tour | 2.Pro |
| 27 | 2021-06-05 | Dwars door het Hageland WE | 1.2 |
| 28 | 2021-06-06 | Dwars door de Westhoek | 1.1 |
| 29 | 2021-06-22 | Lotto Belgium Tour | 2.1 |
| 30 | 2021-06-26 | La Course by Le Tour de France | 1.WWT |
| 31 | 2021-07-02 | Giro d'Italia Internazionale Femminile | 2.Pro |
| 32 | 2021-07-08 | Baloise Ladies Tour | 2.1 |
| 33 | 2021-07-31 | Donostia San Sebastian Klasikoa Women | 1.WWT |
| 34 | 2021-08-12 | Ladies Tour of Norway | 2.WWT |
| 35 | 2021-08-24 | Simac Ladies Tour | 2.WWT |
| 36 | 2021-09-02 | Madrid Challenge by La Vuelta | 2.WWT |
| 37 | 2021-09-08 | Tour Cycliste Féminin International de l'Ardèche | 2.1 |
| 38 | 2021-10-02 | Paris-Roubaix Femmes | 1.WWT |
| 39 | 2021-10-04 | The Women's Tour | 2.WWT |
| 40 | 2021-10-15 | La Classique Morbihan | 1.1 |
| 41 | 2021-10-16 | Grand Prix du Morbihan Féminin | 1.1 |