Best time trial competitors based on the PCS time trial ranking.
| Pos. | Rider | Team | Points | Time trial ranking position |
|---|---|---|---|---|
| 1 | Nibali Vincenzo | Bahrain Merida Pro Cycling Team | 262 | 23 |
| 2 | Mullen Ryan | Trek - Segafredo | 242 | 29 |
| 3 | Ganna Filippo | UAE Team Emirates | 126 | 74 |
| 4 | Cavagna Rémi | Quick-Step Floors | 109 | 88 |
| 5 | de la Parte Víctor | Movistar Team | 103 | 94 |
| 6 | Rodriguez José Luis | Sindicato de Empleados Públicos of San Juan | 90 | 114 |
| 7 | Alzate Carlos | UnitedHealthcare Pro Cycling Team | 84 | 120 |
| 8 | Prado Ignacio de Jesús | Canel's - Specialized | 72 | 144 |
| 9 | Cattaneo Mattia | Androni Giocattoli - Sidermec | 69 | 154 |
| 10 | Vargas Walter | Medellín | 68 | 159 |
| 11 | Boivin Guillaume | Israel Cycling Academy | 62 | 182 |
| 12 | Sevilla Óscar | Medellín | 50 | 237 |
| 13 | García Cortina Iván | Bahrain Merida Pro Cycling Team | 46 | 250 |
| 14 | Najar Gonzalo | Sindicato de Empleados Públicos of San Juan | 46 | 256 |
| 15 | Melivilo Juan Javier | Equipo Continental Municipalidad de Pocito | 45 | 268 |
| 16 | Pantano Jarlinson | Trek - Segafredo | 42 | 283 |
| 17 | Villalobos Román | Canel's - Specialized | 41 | 294 |
| 18 | Cano Alex | Coldeportes Zenu Sello Rojo | 32 | 369 |
| 19 | Eaton Daniel | UnitedHealthcare Pro Cycling Team | 30 | 428 |
| 20 | Muller Mauricio | Sindicato de Empleados Públicos of San Juan | 30 | 396 |